

A few info about Colchicine drug should be said:
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For acute gout flares in patients taking protease inhibitors: Recommended dosing is 0.6 mg as 1 dosage, followed by 0.3 mg 1 hour later. This dosage should be repeated no earlier than 3 days. For patients taking fosamprenavir without ritonavir, the suggested dose is 1.2 mg as 1 dose. This dosage should be repeated no earlier than 3 days.
Liver dosage Adjustments. Familial Mediterranean Fever: Mild to moderate hepatic impairment: No dose adjustment required, but patients should be monitored closely for adverse effects. dose reduction may be necessary. Severe hepatic impairment: dosage reduction should be considered. In patients with hepatic impairment who are taking protease inhibitors for the treatment of HIV-1 infection, the FDA has recommended against the coadministration of Colchicine.
FDA pregnancy category C. It is not known whether Colchicine will harm an unborn baby. Tell your health care professional if you are pregnant or plan to become pregnant while using this medication. It is not known whether Colchicine (Colcrys) passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your healthcare professional if you are breast-feeding a baby.
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And here are some opinions about Colchicine medication from different men and women:
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I had better and faster results when I was taking the generic Colchicine.Colchicine (Colcrys) is slower to react to my flareups. Taking several days to obtain relief as opposed to several hours with the generic Colchicine (Colcrys).
Colchicine (Colcrys) for Gout, Acute: Gout is so painful. After first doses of Colchicine had immediate relief. I had fallen on my knee and was being treated for osteoarthritis with no relief. Went to arthritis doctor who told me it was gout in my knee. Went on Colcyrs and I can walk again.
I recently switched from generic Colchicine to Colchicine (Colcrys), from AR Scientific, for long term treatment of Familial Mediterranean Fever. So far the Colchicine (Colcrys) has helped reduce my symptoms better than the generic Colchicine (Colcrys). The side effects so far have been the same as with Colchicine. The price is higher, but hopefully that will mean a more consistant product.
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Also if you're not sick of reading - here are a few interesting quotes about health from various well-known people:
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Logain Clendening: If you do everything you should do, and do not do anything you should not do, you will, according to the best available statistics, live exactly eighteen hours longer than you would otherwise.
Laurence Sterne: People who are always taking care of their health are like misers, who are hoarding a treasure which they have never spirit enough to enjoy.
Victoria Wood: I sometimes think that being widowed is God's way of telling you to come off the Pill.
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And here we have even more words about Colchicine pills should be recalled:
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Renal dose Adjustments. Familial Mediterranean Fever: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. dosage reduction may be necessary. Severe (CrCl less than 30 mL/min) renal impairment: Dosage should be started at 0.3 mg/day; any increase in dosage should be done with adequate monitoring of the patient for adverse effects. In patients with renal impairment who are taking protease inhibitors for the treatment of HIV-1 infection, the FDA has recommended against the coadministration of Colchicine (Colcrys).
Colchicine Nervous system side effects have rarely included myopathy, seizures, mental status changes, and neuropathy in patients with impaired renal function, and are sometimes reversible with drug discontinuation. Neuromyopathy occurrence has been reported with or without elevated muscle enzymes.
Familial Mediterranean fever (FMF) in patients taking protease inhibitors: FDA recommends a maximum daily dosage of Colchicine (Colcrys) of 0.6 mg (may be given as 0.3 mg 2 times a day). For patients taking fosamprenavir without ritonavir, the maximum daily dosage of Colchicine is recommended to be no more than 1.2 mg (may be given as 0.6 mg 2 times a day).
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And of course more experiences about Colchicine medicine from different men and women:
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Colchicine (Colcrys) for Gout, Acute: Reduced initial pain extremely fast. 3 days later had mildly loose stools, slightly crampy stomach.
I take 0.6 mg daily, and it's working like a charm! Some GI upset (nausea, diarrhea), but worth it! I've been flare free since starting it, and even my body/joint pain is gone.
I have taken Colchicine (Colcrys) off and on during flares, and it seems that it has helped , but it sure makes intestinal problems. I don't want to go out anywhere while taking this medication.
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