

Some words about Colchicine (Colcrys) pills should be said:
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Colchicine (Colcrys) Nervous system side effects have rarely included myopathy, seizures, mental status changes, and neuropathy in patients with impaired renal function, and are sometimes reversible with drug discontinuation. Neuromyopathy occurrence has been reported with or without elevated muscle enzymes.
Renal dose Adjustments. Gout Flares: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. Severe (CrCl less than 30 mL/min) renal impairment: No dose adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.
The current FDA-approved dose for gout flare is substantially lower than what has been historically used clinically. doses higher than 1.8 mg over a 1 hour period for gout flare are not proven more effective and are not recommended.
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And here are a few feedbacks about Colchicine tablets from various patients:
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I do feel this works pretty steady for me.. Not really any stomach issues, just the occassional need to use the toilet often... so I time it and usually stay home when taking this. Im sure to drink lots of water.
I thought gout so I talked to the healthcare professional again and she looked at it and said possible gout and Rx'ed me with Colchicine for 5 days. AFTER 2 DAYS I WAS PAIN FREE!! NO PAIN IN MY FEET, SHOULDERS, ELBOWS, KNEES, HANDS, MUSCLES. ANYWHERE. I COULD RUN UP AND DOUM THE STEPS. This was a miricle to me. I have been pain free up till about 2 wks. ago. I am breaking down and giong to have the uric acid blood test. If it is gout then she will Rx allipurinol(sp)? If I dont have gout then I dont know what I do have but Colchicine was my miracle drug.
I only use it PRN when Im having a flare up and it really seems to help. I also use it with a steroid cream and it makes it work even better!
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Also if you're not sick of reading - here are a few in some way funny words connected with health from different well-known men and women:
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Joseph Addison: Physique, for the most part, is nothing else but the Substitute of Exercise or Temperance.
John Armstrong: Know, then, whatever cheerful and serene supports the mind supports the body too.
Matthew Perry: Vicodin, I got addicted to that little pill. The reason I don't talk about it too much in the press is because it isn't funny, and I love to be funny in interviews. If you joke about that period in your life, it doesn't seem right.
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And here we have more facts about Colchicine (Colcrys) medicine should be recalled:
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Colchicine (Colcrys) Musculoskeletal side effects have been reported the most frequently. These have included myopathy, manifested as weakness, neuropathy, and paralysis.
Colchicine affects the way the body responds to uric acid crystals, which reduces swelling and pain. Generic forms of Colchicine have been used to treat or prevent attacks of gout, or to treat symptoms of Behcets syndrome (such as swelling, redness, warmth, and pain).
Familial Mediterranean fever (FMF) in patients taking protease inhibitors: FDA recommends a maximum daily dose of Colchicine (Colcrys) of 0.6 mg (may be given as 0.3 mg 2 times a day). For patients taking fosamprenavir without ritonavir, the maximum daily dose of Colchicine (Colcrys) is recommended to be no more than 1.2 mg (may be given as 0.6 mg 2 times a day).
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And of course a few more reviews about Colchicine (Colcrys) tabs from different people:
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While on Azathioprine my awesome Rheumatologist suggested Colchicine (Colcrys) because my mucosal ulcerations were not going away. This worked wonders and since I have been on it have had constant dependable results. I am off the Azathioprine and on Humira but still taking Colchicine. This drug I have to say has given me the most improvement of my quality of life.
I take a .6mg tab of Colchicine in the a.m. It has been very helpful in relieving what was my greatest challenge, searing pain in the ankles whenever weightbearing. Has given me a new lease on life. Sorry it took so long to find (9years) and 3 rheumatologists to find out about it.
Colchicine for Gout, Prophylaxis: This is a great drug for gout flareups. The problem is that the cost went from 5 cents per pill to $5.50 per pill
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