

Some words about Colchicine medication should be recalled:
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Patients with renal or liver impairment should not be given Colchicine in conjunction with P-gp or strong CYP450 3A4 inhibitors. In these patients, life-threatening and fatal Colchicine (Colcrys) toxicity has been reported with Colchicine (Colcrys) taken in therapeutic dosages.
Check with your health care professional if any of these most common side effects persist or become bothersome: diarrhea; nausea; stomach pain; vomiting.
Colchicine Renal side effects have included acute renal failure and rare cases of rapid progressive glomerulonephritis. Chronic renal failure and acute renal failure with a fatal outcome following Colchicine toxicity have been reported.
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And here are a few testimonials about Colchicine medication from various people:
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I have FMF and have been on Colchicine for over 4 years now and its a miracle pill. I don't know what I would do without it. It has given me NO side effects! Very inexpensive and easy to swallow...
Not only has this drug used on a daily basis eliminated all experiences with gout, I had a fairly bad case of psoriasis on my hands. With the use of Colchicine my hands completely cleared. Just to make sure that I was not experiencing some new and temporary reaction that led to this psoratic relief, I discontinued the use of the colchincine. The psoriasis in my hand return almost immediately. Upon returning to the use of Colchicine (Colcrys), my hands cleared up once again. Every doctor I have talked to dismisses this because they say that gout and psoriasis are not related. Thats fine, but the bottom line is that this drug suppresses both my gout and psoriasis.
Colchicine for Gout, Acute: Gout is so painful. After first doses of Colchicine had immediate relief. I had fallen on my knee and was being treated for osteoarthritis with no relief. Went to arthritis health care professional who told me it was gout in my knee. Went on Colcyrs and I can walk again.
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Also if you're not tired of reading - here are a few interesting expressions about health and medications from different famous people:
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Paul Farmer: We've taken on the major health problems of the poorest - tuberculosis, maternal mortality, AIDS, malaria - in four countries. We've scored some victories in the sense that we've cured or treated thousands and changed the discourse about what is possible.
Jean Piaget: I have always detested any departure from reality, an attitude which I relate to my mother's poor mental health.
Gene Tierney: I ask myself: Would I have been any worse off if I had stayed home or lived on a farm instead of shock treatments and medication?
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And here we have some more words about Colchicine (Colcrys) medication in general:
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Colchicine Dermatologic side effects have included urticaria, alopecia after intoxication or long-term usage, toxic epidermal necrolysis with concomitant ethanol use, fixed drug eruption, dermatitis, and purpura.
The current FDA-approved dose for gout flare is substantially lower than what has been historically used clinically. dosages higher than 1.8 mg over a 1 hour period for gout flare are not proven more effective and are not recommended.
Usual Pediatric dose for Familial Mediterranean Fever. Oral: 4 to 6 years - 0.3 to 1.8 mg daily, administered in 1 or 2 divided doses. 6 to 12 years: 0.9 to 1.8 mg daily, administered in 1 or 2 divided doses. Over 12 years: 1.2 to 2.4 mg daily, administered in 1 or 2 divided doses. The dose should be increased as needed to control disease and as tolerated in increments of 0.3 mg/day to a maximum recommended daily dosage. If intolerable side effects develop, the dose should be decreased in increments of 0.3 mg/day.
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And of course more reviews about Colchicine tabs from some patients:
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While on Azathioprine my awesome Rheumatologist suggested Colchicine (Colcrys) because my mucosal ulcerations were not going away. This worked wonders and since I have been on it have had constant dependable results. I am off the Azathioprine and on Humira but still taking Colchicine. This drug I have to say has given me the most improvement of my quality of life.
Colchicine for Behcet's Disease: Been using Colchicine for over 20 years. No noticeable side effects but do get my bloods checked annually. Only problem was when returned to using it after a two year break. Some diarrhea at first but this stopped after a few weeks once body built up tolerance to drug.
I only use it PRN when Im having a flare up and it really seems to help. I also use it with a steroid cream and it makes it work even better!
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