

A few info about Colchicine (Colcrys) pills should be mentioned:
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Patients with renal or liver impairment should not be given Colchicine in conjunction with P-gp or strong CYP450 3A4 inhibitors. In these patients, life-threatening and fatal Colchicine toxicity has been reported with Colchicine (Colcrys) taken in therapeutic doses.
Usual Adult dosage for Constipation - Chronic - 0.6 mg orally three times daily for 4 weeks. Usual Adult dose for Sweet's Syndrome - 0.6 mg orally twice daily.
Colchicine Musculoskeletal side effects have been reported the most frequently. These have included myopathy, manifested as weakness, neuropathy, and paralysis.
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And here are some experiences about Colchicine tablets from different patients:
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Been on it for almost 3 months now for reacurring pericarditis. It has helped lesson the pain when i have a flare up, so it does help. But had to get my dosage right first, had horrible side effects until i figured out my dose!
Colchicine (Colcrys) for Gout, Acute: I get several gout attacks a year. Less side effects but also not as fast acting as Colchicine (Colcrys) was. Taking more Colcry over several days to obtain relief then when I was taking Colchicine (Colcrys).
I take 0.6 mg daily, and it's working like a charm! Some GI upset (nausea, diarrhea), but worth it! I've been flare free since starting it, and even my body/joint pain is gone.
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Also if you're not tired of reading - here are a few informative quotes about health from different widely known people:
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William Hazlitt: Look up, laugh loud, talk big, keep the color in your cheek and the fire in your eye, adorn your person, maintain your health, your beauty and your animal spirits.
Plautus: He whom the gods love dies young, while he is in health, has his senses and his judgments sound.
John Henry Cardinal Newman: Health of body and mind is a great blessing, if we can bear it.
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And here we have more facts about Colchicine medicine should be said:
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Before taking Colchicine (Colcrys), tell your doctor if yo have liver or kidney disease, heart disease, a stomach ulcer, ulcerative colitis, Crohn's disease, intestinal bleeding, or any other severe gastrointestinal disorder. If you take Colchicine over a long period of time, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.
Renal dosage Adjustments. Familial Mediterranean Fever: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dose adjustment required, but patients should be monitored closely for adverse effects. dose reduction may be necessary. Severe (CrCl less than 30 mL/min) renal impairment: Dosage should be started at 0.3 mg/day; any increase in dosage should be done with adequate monitoring of the patient for adverse effects. In patients with renal impairment who are taking protease inhibitors for the treatment of HIV-1 infection, the FDA has recommended against the coadministration of Colchicine.
The current FDA-approved dosage for gout flare is substantially lower than what has been historically used clinically. doses higher than 1.8 mg over a 1 hour period for gout flare are not proven more effective and are not recommended.
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And of course more reviews about Colchicine (Colcrys) medicine from some men and women:
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Colchicine (Colcrys) for Gout, Acute: Reduced initial pain extremely fast. 3 days later had mildly loose stools, slightly crampy stomach.
I take a .6mg tab of Colchicine (Colcrys) in the a.m. It has been very helpful in relieving what was my greatest challenge, searing pain in the ankles whenever weightbearing. Has given me a new lease on life. Sorry it took so long to find (9years) and 3 rheumatologists to find out about it.
It helps with the joint pain and mouth sores a bit. I get the sores less since I started treatment. I was suppose to take it twice a day but it made me quite ill.
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