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Colchicine Dermatologic side effects have included urticaria, alopecia after intoxication or long-term usage, toxic epidermal necrolysis with concomitant ethanol use, fixed drug eruption, dermatitis, and purpura.
Renal dose Adjustments. Gout Flares: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dose adjustment required, but patients should be monitored closely for adverse effects. Severe (CrCl less than 30 mL/min) renal impairment: No dosage adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.
Colchicine (Colcrys) Musculoskeletal side effects have been reported the most frequently. These have included myopathy, manifested as weakness, neuropathy, and paralysis.
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I am a male 67 years old with the customary ailments of a person of this age. I have experienced the painful condition of gout in my big toes in the past 4 years or so & did not know there was some medication that would have relieved my pain. However the last time I had an attack I was forced to seek medical treatment. My doctor precribed Colchicine (Colcrys) & to make a long story short, I had almost 90% relief within 12 hours. No side affects whatsoever. It works.
I had better and faster results when I was taking the generic Colchicine (Colcrys).Colchicine (Colcrys) is slower to react to my flareups. Taking several days to obtain relief as opposed to several hours with the generic Colchicine.
Colchicine (Colcrys) for Gout, Acute: Gout is so painful. After first doses of Colchicine had immediate relief. I had fallen on my knee and was being treated for osteoarthritis with no relief. Went to arthritis healthcare professional who told me it was gout in my knee. Went on Colcyrs and I can walk again.
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John Armstrong: Know, then, whatever cheerful and serene supports the mind supports the body too.
B. B. King: The way I feel today, as long as my health is good and I can handle myself well and people still come to my concerts, still buy my CDs, I'll keep playing until I feel like I can't.
Rod Blagojevich: Our children's health and well-being are dependent on our commitment to promoting food access and good eating habits at home, at school and in the community.
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FDA pregnancy category C. It is not known whether Colchicine (Colcrys) will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether Colchicine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Dialysis. Gout Flares: The recommended dose for patients undergoing dialysis should be reduced to a single dosage of 0.6 mg. For these patients, a treatment course should not be repeated more than once every 2 weeks.
For acute gout flares in patients taking protease inhibitors: Recommended dosing is 0.6 mg as 1 dose, followed by 0.3 mg 1 hour later. This dose should be repeated no earlier than 3 days. For patients taking fosamprenavir without ritonavir, the suggested dose is 1.2 mg as 1 dosage. This dosage should be repeated no earlier than 3 days.
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And of course some more feedbacks about Colchicine medicine from different patients:
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Really helps knock down the acute attacks of gout. doctor says as soon as I start getting sick is time to stop taking it.
I have been taking this drug for 2 years now and without it my joints just cease right up. To begin with I felt sick but now I have no side effects
I have FMF and have been on Colchicine for over 4 years now and its a miracle pill. I don't know what I would do without it. It has given me NO side effects! Very inexpensive and easy to swallow...
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