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Colchicine Hematologic side effects have included thrombocytopenia, pancytopenia, leukopenia, agranulocytosis, bone marrow failure, bone marrow depression, disseminated intravascular coagulation, and aplastic anemia in patients on long-term therapy and are most common in cases of overdose or intoxication. Heinz-body hemolytic anemia has been reported in 3 cases.
Seek medical attention right away if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; infection; numbness or tingling; severe diarrhea; sore throat; tiredness; unusual bleeding or bruising; weakness.
Usual Adult dosage for Biliary Cirrhosis - 0.6 mg orally twice a day. Usual Adult dosage for Sarcoidosis - 0.6 mg orally twice a day. Usual Adult dosage for Pseudogout - Prophylaxis - 0.6 mg orally twice a day.
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I recently switched from generic Colchicine to Colchicine, from AR Scientific, for long term treatment of Familial Mediterranean Fever. So far the Colchicine (Colcrys) has helped reduce my symptoms better than the generic Colchicine. The side effects so far have been the same as with Colchicine. The price is higher, but hopefully that will mean a more consistant product.
I only take it when I feel an impending attack, and it is amazing. It does cause some diahrrea after 3 days of treatment, but is well worth it, instead of enduring the excruciating pain associated with gout attack. A magic pill indeed.
I thought gout so I talked to the health care professional again and she looked at it and said possible gout and Rx'ed me with Colchicine for 5 days. AFTER 2 DAYS I WAS PAIN FREE!! NO PAIN IN MY FEET, SHOULDERS, ELBOWS, KNEES, HANDS, MUSCLES. ANYWHERE. I COULD RUN UP AND DOUM THE STEPS. This was a miricle to me. I have been pain free up till about 2 wks. ago. I am breaking down and giong to have the uric acid blood test. If it is gout then she will Rx allipurinol(sp)? If I dont have gout then I dont know what I do have but Colchicine was my miracle drug.
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Alonzo Clark: Every man's disease is his personal property.
Benjamin Disraeli: The health of the people is really the foundation upon which all their happiness and all their powers as a state depend.
Clarence Day: A moderate addiction to money may not always be hurtful; but when taken in excess it is nearly always bad for the health.
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Usual Adult dosage for Constipation - Chronic - 0.6 mg orally three times daily for 4 weeks. Usual Adult dosage for Sweet's Syndrome - 0.6 mg orally twice daily.
Usual Adult dosage for Gout - Prophylaxis - Oral: 0.5 to 0.6 mg orally once a day for 3 to 4 days a week (less than 1 attack/year). 0.5 to 0.6 mg orally once a day (greater than 1 attack/year). Severe cases may require 1 to 1.8 mg/day.
Colchicine (Colcrys) Nervous system side effects have rarely included myopathy, seizures, mental status changes, and neuropathy in patients with impaired renal function, and are sometimes reversible with drug discontinuation. Neuromyopathy occurrence has been reported with or without elevated muscle enzymes.
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And of course some more reviews about Colchicine (Colcrys) pills from various people:
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I was a virgin gout sufferer and the health care professional gave me the perscription and reduced the swelling immediately. I am very pleased with the drug and will keep it close by always. No diarria or stomach problems.
I take 0.6 mg daily, and it's working like a charm! Some GI upset (nausea, diarrhea), but worth it! I've been flare free since starting it, and even my body/joint pain is gone.
This is my 3rd and worse bout with gout. My Dr. prescribed this medication and forewarned me that it MAY cause diarahea. He suggested one 0.6 mg pill every four hours instead of every one to two hours. It took just a little longer but after taking this for 18 hours the front of my foots swelling has gone down 50% and the pain has subsided by over 75%. When this attack is over , he is starting my on Allopurinol to avoid this in the future. In short, Colchicine is a god sent medication.
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