

Several words about Colchicine (Colcrys) medicine anyone should know:
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Renal dosage Adjustments. Gout Flares: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. Severe (CrCl less than 30 mL/min) renal impairment: No dosage adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.
Colchicine (Colcrys) affects the way the body responds to uric acid crystals, which reduces swelling and pain. Generic forms of Colchicine (Colcrys) have been used to treat or prevent attacks of gout, or to treat symptoms of Behcets syndrome (such as swelling, redness, warmth, and pain).
Colchicine (Colcrys) Gastrointestinal side effects have included diarrhea, nausea, vomiting, and abdominal pain in nearly 80% of treated patients, and can be indicative of acute Colchicine (Colcrys) toxicity. Anorexia, electrolyte disturbance, pancreatitis, and paralytic ileus may also occur, and steatorrhea and enzyme inhibition have been reported in patients on long-term Colchicine (Colcrys) prophylaxis.
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And here are some experiences about Colchicine (Colcrys) tabs from some patients:
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This is my 3rd and worse bout with gout. My Dr. prescribed this medication and forewarned me that it MAY cause diarahea. He suggested one 0.6 mg pill every four hours instead of every one to two hours. It took just a little longer but after taking this for 18 hours the front of my foots swelling has gone down 50% and the pain has subsided by over 75%. When this attack is over , he is starting my on Allopurinol to avoid this in the future. In short, Colchicine (Colcrys) is a god sent medication.
I recently switched from generic Colchicine (Colcrys) to Colchicine, from AR Scientific, for long term treatment of Familial Mediterranean Fever. So far the Colchicine has helped reduce my symptoms better than the generic Colchicine (Colcrys). The side effects so far have been the same as with Colchicine (Colcrys). The price is higher, but hopefully that will mean a more consistant product.
I only use it PRN when Im having a flare up and it really seems to help. I also use it with a steroid cream and it makes it work even better!
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Also if you're not sick of reading - here are several in some way funny expressions about health from different well known persons:
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John Mortimer: I refuse to spend my life worrying about what I eat. There is no pleasure worth forgoing just for an extra three years in the geriatric ward.
Corrine Brown: Today right here in America we have 50 million people without health insurance.
Meryl Streep: It's bizarre that the produce manager is more important to my children's health than the pediatrician.
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And here we have more information about Colchicine medicine in general:
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Colchicine Nervous system side effects have rarely included myopathy, seizures, mental status changes, and neuropathy in patients with impaired renal function, and are sometimes reversible with drug discontinuation. Neuromyopathy occurrence has been reported with or without elevated muscle enzymes.
Usual Adult dose for Aphthous Stomatitis - Recurrent - 0.5 to 0.6 mg orally daily. The dose may be titrated upward while the patient is observed for signs of toxicity.
Before taking Colchicine, tell your health care professional if yo have liver or kidney disease, heart disease, a stomach ulcer, ulcerative colitis, Crohn's disease, intestinal bleeding, or any other severe gastrointestinal disorder. If you take Colchicine (Colcrys) over a long period of time, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.
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And of course a few more feedbacks about Colchicine (Colcrys) tablets from various patients:
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I have taken Colchicine off and on during flares, and it seems that it has helped , but it sure makes intestinal problems. I don't want to go out anywhere while taking this medication.
Colchicine (Colcrys) for Gout, Prophylaxis: Unusual medication, but works fast and effectively, totally removing gout symptoms.
I have been suffering from gout for past 10 years. One instance the pain was so bad I had to call the on call physician. I was diagnosed with gout. I was prescribed Colchicine for the pain. The pain stopped and the swelling decreased. I now take the medication daily and have no problems. I have no complains since I have been on this medication. I'll deal with the side effects of the medication than the severe pain from the gout which is unbearable.
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